# Lipid Nanoparticles in mRNA Vaccines: Structure and Side Effect Claims - Original post: https://www.twitter.com/i/status/2120055437227880487 - Source account: [@apolut_net](https://x.com/apolut_net) - Source language: German - Target language: English - Duration: 6:03 - Published: 2026-11-10 - Machine translated. Check the original before quoting. - Canonical URL: https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims - Original-language version: https://www.translate.mom/transcript/gHas0N15w3gF/de/lipid-nanopartikel-in-mrna-impfstoffen-aufbau-und-nebenwirkungsbehauptungen.md ## Transcript [0:01](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=1) If we're right, then, uh, the side-effect profile you've seen so far wasn't the end of the story. [0:09](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=9) That means we're talking here about side effects related to all kinds of, uh, dysfunctions in the human body after this alleged vaccination. [0:21](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=21) That means, uh, we've now seen things like very rare things that normally don't occur at all. [0:26](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=26) Testicular cancer in athletes, somehow. Right. [0:29](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=29) Then, uh, repeatedly, uh, repeatedly, uh, people simply collapsed on the field. [0:34](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=34) We've already seen that in droves. Those are probably the, the, uh— well, those are the low-hanging fruit, the things that would happen anyway. [0:43](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=43) Right, but lots and lots of other things, where autoimmune reactions occur, and all sorts of things, where cells suddenly go haywire in the body, um, and cytokine storms, to name just a few things. [0:55](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=55) And, um, it looks like you've, uh, well, f-found the missing link, uh, which, alongside this, um, mRNA effect, mod-mRNA effect, now shows what's else going on in the body. [1:10](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=70) So, now, uh, we can see here, um, on the screen a liquid nano, uh, a lipid nanoparticle. [1:17](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=77) I keep stumbling over it every time now. [1:19](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=79) Lipid nanoparticle. Um, uh, and, uh, now, now, as a biologist, you quickly picture it like this. [1:27](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=87) Yeah, it's a little bubble. So I've got, like, a layer of fat around the outside and in the middle there's some kind of liquid And somewhere in this liquid, maybe there's just one tiny bubble left, and then this, this modRNA is floating around in there and everything is perfectly fine. [1:42](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=102) Because somehow, I already know this from biology. [1:44](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=104) It's all so very, very fine. Uh, so biology can handle that. [1:49](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=109) Uh, and then I talked to you, and you said: Uh, the idea is, um, completely wrong. [1:56](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=116) Yeah. Um, and the thing is, um, imagine the whole thing, um, as what you see here. [2:03](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=123) Um, what looks like a solid, uh, sphere here isn't a solid sphere. [2:07](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=127) It's a state made up of, uh, individual, tiny lipid particles that dance around each other, uh, restructure themselves, and wobble like a kind of soap bubble. [2:19](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=139) And, uh, the real kicker is: There are no covalent bonds in that thing. [2:23](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=143) So that means a chemical bond. Uh, that means the things somehow stick firmly together, but instead there are purely weak physical interactions that somehow keep them sort of stable. [2:34](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=154) And, uh, you have a liquid core again. So there's no, uh, um, no cavity in there, uh, somehow, that, that, um, is filled with, with something th-that binds it more firmly, uh, uh, f-filled, but you only have your individual lipids, [2:51](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=171) which somehow structurally, um, hold together all the way to the very core, um. [2:59](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=179) Uh, th-that means what you perceive here as a cavity is actually packed full of the individual lipid components. [3:05](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=185) Though the PEGylated lipids are definitely more at the sur— uh, at the interface. [3:11](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=191) Um, what you see here as the surface, It isn't a real surface, but just certain distances, which then, um, altogether, under the microscope, look something like a sphere. [3:21](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=201) Um. Now you've used another term again. PEGylated, uh, uh— Those are the blue little beads with the extra-long fatty tails. Um. [3:29](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=209) Exactly, so that's, um, polyethylene glycol, or PEG. Exactly. [3:33](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=213) Um, and, uh, just to mention it. So these are very specific types of, uh, of, of these, uh, phospho— uh, —lipids. [3:41](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=221) And, uh, the interesting thing is that, um, there's a mixture here of phospholipids modeled on natural ones and, uh, completely artificial phospholipids—Right. —appearing. [3:53](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=233) Um, and you told me, I should imagine this bubble as also folding in on itself, like that. and then, and then it k-k-keeps turning in on itself, all the time. [4:02](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=242) And— Exactly. —somehow, uh, uh, um, I can never tell which Fos-phospholipid is facing outward at any given point, so which type of phospholipid is facing outward and whether something else is facing outward too. So these, um, uh, [4:14](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=254) spheres have very strange properties on the outside. [4:17](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=257) So you never know exactly what they look like. [4:19](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=259) So, sort of these biomonsters, basically. Right. [4:22](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=262) Um, the thing is, um, this restructuring happens, uh, especially when a phase change occurs. [4:28](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=268) That is, when something in the external conditions or the physical forces acting on this thing from outside, uh, changes. [4:35](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=275) Because they're just weak physical forces, uh, that hold things together, that hold the individual particles together. [4:42](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=282) That's roughly how you have to imagine it. [4:46](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=286) And, um, what's also not entirely clear yet, um, well, um, you can see these, um, these individual little bubbles inside, where the modRNA is then encapsulated or not. [5:01](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=301) Um, that's the ideal, w-what you see here. [5:06](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=306) So, um, lipid nanoparticles, you talk about a um, filled or, um, loaded lipid nanoparticle if you have, like, um, between four and six, uh, RNA strands packed into this thing. [5:17](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=317) So, but the problem is, these are pure, um, probabilities. [5:22](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=322) That means you have between, and these really are the completely official figures, Um, that have ever, um, been measured. [5:31](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=331) Um, you have between 12 and 80% between— l-let that sink in— um, um, between 12 and 80% variance empty lipid nanoparticles, um, that carry either one strand or no strand at all. [5:57](https://www.translate.mom/transcript/gHas0N15w3gF/en/lipid-nanoparticles-in-mrna-vaccines-structure-and-side-effect-claims?t=357) Apolut. Now more than ever.