Transcript · English → Chinese
English → Chinese transcript
使用电子显微镜，你能多容易地区分 这些
逆转录病毒？
因为它们在像我这样的外行眼里看 起来都一样。
当然不是。
我可以在半小时内教会你。
我们把这些结构差异做了一个清晰 的总结。
你可以进行测量。
如果你开始测量核糖核蛋白— —它是基因组和一些
蛋白组成的复合体，它在病毒颗粒中 在哪里？在出芽阶段，还是在未成熟颗粒中？
在成熟颗粒和未成熟颗粒中，它是如 何组织的？
那糖蛋白呢？
这些问题都可以用定量方法评估。
所以你确实可以做出一个客观的诊 断。
所以，对你这样的人来说，很容易分 辨出区别。
锥形的核心很容易识别。
看起来和C型很不一样，对吗？
嗯。
完全是。
或者至少对受过训练的人来说。
不，不。
你会看出来的。
在你看来，为什么Gallo和Montagnier看 到的是C型而不是lenti？
当他们在电子显微镜下观察时？
因为他们脑子里已有那种印象。
哦，他们看到了自己想看到的？
是的。
哦。
不过，纯化仍然是最大的问题。
纯化。
如果你没有经过纯化的话…
如果你没有好的纯化，正如Montagnier 所说的…
End of transcript · 225 words · machine translated
Original transcript (English)
Using the electron microscope, how easy is it for you to differentiate between all these retroviruses? Because they all look, to someone like me, the untrained eye, they all look the same. Certainly not. I will be able to teach you within half an hour.
We have made a nice summary on these structural differences. You can measure. If you start measuring the ribonucleoprotein, that's the complex of the genome and some protein, where is it in the virion, in the budding, in the immature particle? How is it organized in the mature particle versus the immature particle?
What about the glycoproteinopsis? These are questions that can be quantitatively assessed. So you really can make an objective diagnosis. So, for someone like you, it's easy to tell the difference. The cone-shaped core is very identifiable.
It looks very different than a C-type, is that right? Yeah. Absolutely. Or at least to the trained eye. No, no.
You will see it. How come, in your opinion, did Gallo and Montagnier see C-type instead of lenti? When they looked under their electron microscopes? Because they had it in the brain. Oh, they saw what they wanted to see?
Yeah. Oh. Still, the purification is the biggest problem. The purification. Once, if you don't have purified...
If you have no good purification, as Montagnier said...
