New Drug Trials for Multiple Sclerosis
A repair drug for multiple sclerosis just cleared its
third trial in a row.
Here's the catch: nobody is celebrating.
Metformin, the diabetes drug, combined with
clemastine, an antihistamine, helps the brain
rebuild the protective coating around nerves that
multiple sclerosis destroys.
This isn't the first time it's worked.
It's the third separate trial now showing this combination
significantly increases myelin repair in people
with relapsing remitting multiple sclerosis.
But here's the honest part.
After six months of treatment, patients showed no
improvement on disability or vision.
The repair is measurably real. The benefit patients
can actually feel isn't there yet.
Now,
that's not necessarily bad news. It might just mean six months
is too short.
The lead researcher on this trial says it could take years for real
myelin repair to translate into less
disability, even if the underlying biology is working
exactly as hoped.
Would you take a drug proven to physically repair damage in your brain,
knowing you might not feel the benefit for years?
Or does "no improvement yet" change how you'd weigh
it? And don't forget, metformin and clemastine is the
easiest and cheapest drug combination that a person can
get.
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