Psilocybin and Advanced Alzheimer's: A Reported Single-Patient Case

Advanced Alzheimer's patient, she regained speech, memory, and bladder control after a single psilocybin dose.

Tell us about this. Yeah. This is absolutely, uh, uh, groundbreaking actually, because for Alzheimer's, we haven't really ever seen a documented case report of somebody with advanced Alzheimer's basically going into at least partial remission, right? And so what they found in this particular case was this was a, an, an elderly woman

with advanced Alzheimer's. She could barely hold a sentence.

She could barely talk. She wet the bed at night.

And they said, "You know what? We're gonna try.

We're gonna give her psilocybin." They gave her five grams of that, okay? That's a very high dose. So she...

And so she literally, like, went into a sleep-like state for 15 hours. But when she woke up from the sleep, um, all of a sudden she could talk again. She remembered words.

She remembered her family. She could speak in full sentences.

She regained her memory. She regained her ability to hold conversations. She even regained her bladder control. She stopped wetting the bed, and she regained mobility.

She could walk again. So it's absolutely crazy, and it's explained by the mechanisms behind it.

So what psilocybin does is it actually increases the growth rate on neurons, right? It actually boosts the literal regeneration of the dendrites on your neurons and helps that connectivity, uh, become stronger. And so in people with Alzheimer's,

it's all damaged. Um, it appears this may be able to kind of restart that, that healing process and lead to these improvements.

So now we obviously need larger studies with way more people than one person, uh, but no Alzheimer's drug has ever done anything close to this.

Mm-hmm. Wow, that is amazing.