Discussion on Pharmacological Dosage Changes

I want to show you something right here.

See this book right here?

This book is called The Pharmacological Basis of Therapeutics

and I want to read something on page 1687.

The maintenance dose usually ranges between 50,000 and 250,000 units daily.

A few years later,

if you look at the textbooks,

it's down to between 400 and 600 IUs.

Maybe it just worked too well and

they had to take it out?

I have no idea.